Michael Rugg, PhD, Integrative Neuroscience COBRE seminar series
The cognitive neuroscience of episodic memory retrieval across the adult lifespan
I will describe findings from a series of fMRI studies that examine the neural regions, networks, and patterns of cortical activity that accompany successful episodic memory retrieval (recollection). I will present evidence that recollection is associated with a consistent pattern of enhanced activity in a ‘core recollection network’ as well as enhanced functional connectivity between the network and a domain-general executive control network. I will also describe findings indicating that recollection is associated with reinstatement in the brain of processes and representations that were active when the recollected event was first experienced. Each of these neural correlates of recollection is largely impervious to the effects of age, at least when older participant samples comprise healthy individuals at low risk for neurodegenerative disease. The implications of these findings for understanding the neural bases of both recollection and age-related episodic memory decline will be discussed.
Friday, October 11 at 1:00pm
Donald W. Reynolds School of Journalism, 101
1664 N. Virginia St.