Discover wonderfully preserved parts of history mixed with picturesque beaches and vibrant cultures on this 10-night journey aboard Oceania Cruises’ Sirena.

Begin your adventure with a few days in Panama City, a city that connects north and south, historic and modern. Then, marvel at the Panama Canal before strolling down the narrow stone walkways of historic Cartagena. Gaze at the white-peaked Sierra Nevada and rest in the sand of the forest-lined beaches of Santa Marta. In Oranjestad, observe the colorful colonial buildings before traveling across the floating bridge in Willemstad. Relax in the quiet, beautiful haven of Port Antonio and become a rum master in George Town or explore the mesmerizing depths of the ocean on a scuba diving excursion.